Cisplatin hyponatriämie

WebJan 1, 2024 · Hyponatremia in cancer patients can be caused by a number of factors including gastrointestinal losses, cardiac failure, diabetes insipidus, cancer-induced physiological changes or hormonal secretion, pulmonary diseases, central nervous system disorders, several drugs other than anticancer treatments (e.g., chlorpropamide, … WebHyponatremia is one of the common electrolyte disorders associated with cisplatin (CDDP) administration. We report here two cases of hyponatremia associated with CDDP. Case 1 : A 75-year-old man with urothelial carcinoma of bladder (cT3N1M0) underwent neoadjuvant chemotherapy with CDDP and gemcitabi …

Chapter 5: Electrolyte and Acid Base Disorders in Malignancy

Webdromes have distinct clinical characteristics and managements. The key differential diagnostic feature for RSWS is the excessive urinary excretion of sodium, whereas the urinary excretion of sodium in SIADH is normal or decreased. The treatment for RSWS is supplement of salt, which is opposite to the treatment of SIADH. We report a case of a … WebJul 7, 2024 · 1 Department of Pharmacy, Showa University Hospital, Tokyo, Japan. 2 Department of Hospital Pharmaceutics, School of Pharmacy, Showa University, Tokyo, Japan. 3 Department of Surgery, Division of General and Gastroenterological Surgery, School of Medicine, Showa University, Tokyo, Japan. 4 Showa University Esophageal … sights to see in normandy france https://thetbssanctuary.com

Profound hyponatremia and dehydration: A case of cisplatin …

WebAug 1, 2002 · We report a case of a patient with hyponatremia and excessive urinary excretion of sodium after cisplatin-based chemotherapy. RSWS was diagnosed and the patient was treated with a sodium supplement. We also summarize the key diagnostic features and the most common differential diagnoses for hyponatremia syndrome. WebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt … WebNov 1, 1997 · Cisplatin is one of the most widely used agents in cancer treatment. Cisplatin regimens can lead to a more or less pronounced hyponatremia in 4 to 10% of cases due to salt wasting with... the prime apts

Renal salt-wasting syndrome in a patient with cisplatin-induced ...

Category:Cisplatin-induced hyponatremia in malignancy: …

Tags:Cisplatin hyponatriämie

Cisplatin hyponatriämie

Cisplatin induced hyponatremia; looking deeper - Renal

WebHyponatremia of grade 3 or above developed in 30.7% of the generic CDDP group compared to 15.1% of the brand-name CDDP group ( P =0.011). Multivariate analysis … WebMar 1, 2024 · A case of an elderly male presenting with significant recurrent hyponatremia, and prerenal azotemia, with recent exposure to cisplatin along with significant hypovolemia and urinary loss of sodium is reported. Cisplatin is a well‐known chemotherapeutic agent that can be associated with hyponatremia. It is known to be associated with a multitude …

Cisplatin hyponatriämie

Did you know?

WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium reabsorption, which in rare cases may lead to hyponatremia via salt wasting nephropathy [ 41 ]. WebOnset of severe hyponatremia following cisplatin (CDDP) administration has been previously reported. However, the risk factors associated with hyponatremia still remain …

Webwhich can induce hyponatremia. As regards platinum, cisplatin is more frequently described than carbopla-tin.[1] The incidence of hyponatremia secondary to cisplatin can be as high as 43%,[6] the mechanism of action by which cisplatin induces hyponatremia is 100 105 110 115 120 125 130 135 140 0 100 200 300 400 500 600 Na + urine (ml/H) … WebMay 19, 2024 · Cisplatin treatment may cause hyponatremia through SIADH, related to both higher secretion of and sensitivity to ADH ( 32 ). Nausea and vomiting, which are common side effects of platinum …

WebHyponatremia due to syndrome of inappropriate antidiuretic hormone secretion (SIADH) or gastrointestinal loss of sodium is sometimes seen during chemotherapy. However, … WebKeywords: Cisplatin, Dehydration, Hyponatremia, Renal salt wasting, Siadh. Case Presentation: A 63-year-old male presents to the hospital with complaints of one-day history of weakness, dizziness. His outpatient blood work demonstrated a serum sodium level of 124 mEq/L, and a creatinine of 3.1 mg/dL. His medical history was significant for high ...

WebMay 22, 2012 · The development of hyponatremia during cisplatin therapy bears special mention. Cisplatin stimulates AVP secretion to cause SIADH, but it can also directly damage renal tubules to interfere with sodium …

WebFeb 1, 1999 · Hypomagnesemia is a well known side-effect in patients receiving cisplatin-containing chemotherapy. Cisplatin induces hypomagnesemia through its renal toxicity possibly by a direct injury to mechanisms of magnesium reabsorption in the ascending limb of the loop of Henle as well as the distal tubule. the prime bankWebJul 20, 2024 · Platinum chemotherapy, particularly cisplatin, is commonly associated with electrolyte imbalances, including hypomagnesemia, hypokalemia, hypophosphatemia, Electrolyte disorders with platinum … the prime arlington apartmentsWebJun 2, 2024 · Group A received cisplatin 60-100 mg/m 2 q 3 weeks with laboratories before day 1, group B received cisplatin 60-75 mg/m 2 q 3 weeks with laboratories before days 1 and 8 of each cycle and group C had weekly cisplatin 40 mg/m 2 and laboratories. Association between hypomagnesemia, hypokalemia, hyponatremia, and risk of AKI, as … the prime apartments arlingtonWebSep 18, 2024 · NCBI Bookshelf the prime appWebNational Center for Biotechnology Information sights to see in phoenix areaWebNational Center for Biotechnology Information sights to see in queenslandWebHyponatremia is a rare complication associated with cisplatin. The mechanism by which it causes hyponatremia is thought to be due to either inducing SIADH or by renal salt wasting syndrome (RSWS) [1]. It is unclear why it occurs but it is believed that pharmacogenetics plays an essential role. the prime arlington