WebCrohn disease begins with crypt inflammation and abscesses, which progress to tiny focal aphthoid ulcers. ... However, with judicious medical therapy and, where appropriate, surgical therapy, most patients function well and adapt successfully. Disease-related mortality is very low. GI cancer, including cancer of the colon and small bowel, is ... WebJan 25, 2024 · An exploding crypt is dilated, lined by a flattened epithelium, and filled with cellular debris [ 3 ]. Star et al.’s definition of a crypt microabscess requires ≥3 apoptotic bodies in the crypt wall, and is classified by its intraluminal cellular content—neutrophilic, eosinophilic, or apoptotic/mixed [ 12 ].
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