The phospholipid composition of cellular membranes has been suggested to be required for the intracellular trafficking of some transporters (Guo et al. 2010; Lee et al. 2012). The endocytosis of mutants was therefore examined using a FM4–64 staining assay. The plasma membrane and septa were quickly … See more The sequences of all enzymes directly involved in the PE and PC biosynthetic pathway in budding yeast were used as queries for BlastP … See more To determine the role of PE and PC biosynthetic genes in asexual reproduction, the number of conidia generated by the individually tested strains in carboxymethyl cellulose (CMC) medium was calculated. All … See more To characterize the function of the above 10 identified PE and PC biosynthetic genes, we generated deletion mutants of each gene using the homologous recombination … See more The virulence of each mutant was evaluated by point inoculation of a conidial suspension on flowering wheat heads. On wheat heads inoculated with the wild-type strain PH-1, scab symptoms first developed on the … See more WebThe fungal phosphatidylserine (PS) synthase, a membrane protein encoded by the CHO1 gene, is a potential drug target for pathogenic fungi, such as Candida albicans . However, both...
Phosphatidylserine decarboxylase is critical for the maintenance …
WebJul 15, 2024 · Indeed, lipid biosynthetic genes such as the phosphatidylserine decarboxylase encoding genes ( PSD1 and PSD2) in C. albicans were reported to influence EV size and protein composition, … WebFeb 20, 2024 · Europe PMC is an archive of life sciences journal literature. head-up tilt
Type II phosphatidylserine decarboxylase is crucial for the …
WebFeb 4, 2010 · Phosphatidylserine synthase and phosphatidylserine decarboxylase are essential for cell wall integrity and virulence in Candida albicans. ... Cho1p is conserved in fungi, but not mammals, so fungal PS synthase is a potential novel antifungal drug target. Full text links . Read article for free, from open access legal sources, via Unpaywall: ... WebOct 1, 2024 · Phosphatidylserine decarboxylases (PSDs) are responsible for catalyzing the production of phosphatidylethanolamine, an important phospholipid in homeostasis, … golf big and tall