Sash1 protein

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August undefined, 2024

Webb6 apr. 2024 · SASH1 contains two predicted nuclear localization signals (NLS1 and NLS2), the conserved Src-homology 3 domain (SH3) and the two sterile alpha-motifs (SAM1 and SAM2). Amino acid residues of the SASH1 coding sequence are indicated. Four deleted SASH1 fragments were cloned to pEGFP-C3 vector and expressed as GFP-deleted … WebbOpen Access Depletion of SASH1, an astrocyte differentiation-related gene, contributes to functional recovery in spinal cord injury Siyi Liu, Siyi Liu Department of Neurosurgery, Affiliated Hospital of Nantong University, Nantong, China Search for more papers by this author Ge Lin, Ge Lin

Immune cell - SASH1 - The Human Protein Atlas

Webb15 juli 2013 · SASH1 is a scaffold molecule in endothelial TLR4 signaling. Recognition of microbial products by TLRs is critical for mediating innate immune responses to … Webb21 mars 2024 · SASH1 (SAM And SH3 Domain Containing 1) is a Protein Coding gene. Diseases associated with SASH1 include Cancer, Alopecia, Pigment Dyscrasia, Onychodystrophy, And Keratoderma and Dyschromatosis Universalis Hereditaria 1 . top 14304 car insurance

Downregulation of SASH1 correlates with tumor progression and …

WebbSASH1 - Wikipedia SASH1 SAM and SH3 domain-containing protein 1 is a protein that in humans is encoded by the SASH1 gene. [5] [6] [7] References [ edit] ^ a b c GRCh38: … Webb31 okt. 2006 · SASH1 is a member of the SH3-domain containing expressed in lymphocytes ( SLY1) gene family that encodes signal adapter proteins composed of several protein–protein interaction domains. The... Webbtration was determined using a Bradford Protein Assay Kit (Beyotime, China). Equal amounts of proteins were loaded and analyzed by standard Western blot (10% reducing SDS-PAGE and 0.2μm PVDF membrane). The membranes with transferred protein were blocked in 5% nonfat dry milk for 2h at RT and incubated with SASH1 or actin primary picking the right motorcycle helmet

Expression of SASH1 in cancer - Summary - The Human Protein …

Webb15 okt. 2024 · SASH1 is a scaffold protein containing SAM (sterile alpha motif) and SH3 domains [19], [20], [21]. The SAM domain, originally observed in drosophila, can dimerize with other SAM or non-SAM domain containing proteins yielding oligomeric platforms for cell signaling involving translocation from the cytoplasm to the nucleus [20], [21]. WebbMETABOLIC SASH1 SINGLE CELL TYPE TISSUES Cell type proteome SINGLE CELL TYPESi Single cell types Group Expression Alphabetical RNA single cell type specificity: Cell type enhanced (Astrocytes, Oligodendrocytes, Adipocytes, Oligodendrocyte precursor cells, Microglial cells) top 1422car insuranceWebbSASH1 gene, which belongs to a member of the SLY family of signal adapter proteins, has been found to suppress the proliferation of tumors. 7 Extensive observations suggested that SASH1 may suppress tumor cell proliferation, migration and invasion in large number of cancer cells. 8–10 In a recent study, authors have demonstrated that autosomal … picking the right macbook pro

"Webb17 mars 2016 · SAM- and SH3-domain containing 1 (SASH1) is a recently identified tumor suppressor gene that is required in the tumorigenesis of breast and other solid carcinomas. The SASH1 protein contains SH3 and SAM domains, indicating that it may serve an important role in intracellular signal transduction. The purpose of the present study was … " - Sash1 protein

Sash1 protein

Exosomal and extracellular HMGB1 have opposite effects on SASH1 …

Webb欧盟知识产权局 . 西班牙. 芬兰 Webb24 feb. 2024 · In the last decade, numerous circRNAs were discovered by virtue of the RNA-Seq technique. With the deepening of experimental research, circRNAs have brought to light the key biological functions and progression of human diseases. CircRNA ITCH has been demonstrated to be a tumor suppressor in numerous cancers, and recently it was …

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WebbAdditonal subcellular location (s) for the encoded protein (s) in human cells. The additional location (s) may not be present i all cell lines and may have lower staining intensity compared to the main location (s). Cytosol (approved) 1 HPA029947: A-431. 2 … Webb8 nov. 2016 · Expression of the SASH1 protein is reduced in a range of human cancers and has been implicated in apoptotic cancer cell death. This study investigated whether …

WebbIntracellular adaptor proteins are indispensable for the transduction of receptor-derived signals, as they recruit and connect essential downstream effectors. The SLy/SASH1 … WebbExpression of SASH1 (dJ323M4.1, KIAA0790, SH3D6A) in cancer tissue. The cancer tissue page shows antibody staining of the protein in 20 different cancers. We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information.

WebbSASH1 mediates sensitivity of breast cancer cells to chloropyramine and is associated with prognosis in breast cancer Burgess JT et al Oncotarget 2016;7(45):72807-72818 … Webb26 mars 2024 · These domains are predominantly found in signaling molecules, adaptors, and scaffold proteins. SASH1 also has an N-terminal 25-residue proline-rich sequence. …

Webb15 okt. 2024 · 2.6. HMGB1 siRNA treatment. We investigated the effects of extracellular HMGB1 on SASH1 gene expression by applying 100 ng/mL of HMGB1 recombinant protein (rHMGB1, 1690-HMB, R&D Systems Co.) to the astrocyte cultures for 60 h and subsequently detecting SASH1 expression through qRT-PCR and WB analysis. The …

WebbSASH1. PROTEIN SUMMARY SECTION OVERVIEW RNA DATA ANTIBODY DATA. SASH1 INFORMATION. Proteini. Full gene name according to HGNC. SAM and SH3 domain … picking the right instant potWebbSASH1 (Q18037095) From Wikidata. Jump to navigation Jump to search. protein-coding gene in the species Homo sapiens ... top 14213 car insuranceWebb21 mars 2024 · GeneCards Summary for SASH3 Gene. SASH3 (SAM And SH3 Domain Containing 3) is a Protein Coding gene. Diseases associated with SASH3 include Immunodeficiency 102 and Combined Immunodeficiency . An important paralog of this gene is SASH1. picking the right motherboardWebb15 maj 2024 · SASH1 protein was expressed in the cytoplasm and nucleus of the placental trophoblast cells, suggesting that SASH1 gene might play a role in abnormal placental development in preeclampsia patients. But it is uncertain whether the upregulation of SASH1 in the placenta is the cause of trophoblast insufficient invasion resulting in … top 14620 car insuranceWebbResults: SASH1 was expressed in human vascular cells (HAECs, smooth muscle cells) and in monocytes/macrophages. Its tissue expression was significantly higher in the … picking the right mattressWebbProtein structure for human protein SASH1 (dJ323M4.1, KIAA0790, SH3D6A) We use cookies to enhance the usability of our website. If you continue, we'll assume that you … picking the right prop for your boatWebbImmune cell - SASH1 - The Human Protein Atlas SASH1 IMMUNE CELL CELL LINEAGES Immune cell proteome IMMUNE CELL TYPE EXPRESSION (RNA)i HPA dataseti Lineage … top 13 the voice 2022